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Blood serum of anonymous donors was obtained from West-Tallinn Central Hospital (Estonia) and the study approval was obtained from Tallinn Medical Research Ethics Committee

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For example, development of click-chemistry approaches using alkynyl acetyl-CoA analogs would provide valuable orthogonal validation and enable spatial visualization of cysteine acetylation in cells

It is imperative to explore novel strategies aimed at reducing MMA levels, considering the limited efficacy of B12 supplementation revealed by our findings