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Changing Attachment Hierarchy 00:52:04 Bereavement Support, Medical Risk 01:05:27 Culture, Alcohol & Death

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Prolonged metabolic stress impairs mitophagy and reduces mitochondrial function, as indicated by decreased oxidative phosphorylation, impaired ATP synthesis, and elevated reactive oxygen species (ROS) generation ( Hepatic lipid overload can also directly initiate inflammatory signaling by activating resident immune cells