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Lin K, Chowdhury S, Zeineddine MA, Zeineddine FA, Hornstein NJ, Villarreal OE, Maru DM, Haymaker CL, Vauthey JN, Chang GJ, Bogatenkova E, Menter D, Kopetz S , Shen JP

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However, the subsequent reperfusion, meant to restore normal blood flow, exacerbates the damage through the formation of reactive oxygen species (ROS), inflammatory mediators, and the activation of numerous signaling pathways (Snchez-Hernndez et al., 2020)