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Talk to your doctor about ways to prevent bone loss (osteoporosis), like taking calcium and vitamin D supplements

Metabolic Regulation of -KGDDs, Genomic Instability, and Vitamin C Isocitrate dehydrogenases (IDHs) are citric acid cycle enzymes responsible for making -KG, and as such are inextricably linked with -KGDD functional activity

J Neurochem 123(2):2938 Smolen JS, Emery P, Ferraccioli GF, Samborski W, Berenbaum F, Davies OR, Koetse W, Purcaru O, Bennett B, Burkhardt H (2015) Certolizumab pegol in rheumatoid arthritis patients with low to moderate activity: the certain double-blind, randomised, placebo-controlled trial

The comorbid mechanisms are complex, posing challenges for clinical treatment

Thus, developing a general catalytic route to access both enantiomers of -hydroxy thioesters is highly desirable