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This conversion directly supports mitochondrial bioenergetics, leading to higher adenosine triphosphate (ATP) levels in hepatocytes (liver cells) and preventing the mitochondrial dysfunction that often accompanies severe toxic burden

Ultimately, tumors exploit this lactateNAD + crosstalk to suppress immune surveillance and establish a protumorigenic, immunosuppressive niche (Fig

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Brangwynne, C

Neuroprotection is generally defined as the use of strategies to prevent, delay, or reverse neuronal injury or dysfunction caused by insults such as ischemia, trauma, or neurodegenerative processes