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MLKL forms a homotrimer through its amino-terminal coiled-coil domain, localizes to the cytoplasmic membrane during TNF-induced necroptosis, and activates downstream TRPM7 to mediate Ca 2+ influx [194]

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10.1016/j.bmcl.2015.02.028 [DOI] [PubMed] [Google Scholar] Xiao X., Chen B., Liu X., Liu P., Zheng G., Ye F., et al

Interestingly, due to increased antioxidant activities, H 2 O 2 and lipid peroxidation marker malondialdehyde levels were similar to those measured in untreated controls after three weeks of treatment

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