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If you follow the standard titration, one 10 mg vial provides: Phase 1 (weeks 1 to 4 at 0.25 mg): uses 1 mg Phase 2 (weeks 5 to 8 at 0.5 mg): uses 2 mg Phase 3 (weeks 9 to 12 at 1.0 mg): uses 4 mg Total through 12 weeks: 7 mg used, 3 mg remaining Remaining 3 mg covers about 1.5 to 2 more weeks at 1.7 mg One vial

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Premature aging is associated with higher levels of 8-oxoguanine and increased DNA damage in the Polg mutator mouse