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The pharmaceutical formulation disclosed herein may comprise hydroxypropyl- alpha-cyclodextrin having a minimum of about 0.4 hydroxypropyls per glucose unit

There is considerable interest in utilizing other strategies to enhance the immunologic effects of GVL for hematologic diseases, particularly MDS/AML, for example with immune checkpoint blockade (ICB), yet success of these approaches has been modest thus far (184)

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However, when cells are infected with coronavirus, there is a reduction of ACE2 receptors on the cell surface and this results in an increase of Ang II which binds to ACE1 and increases ROS levels through NADPH oxidase (Nguyen Dinh Cat et al., 2013)

doi: 10.14499/indonesianjpharm30iss3pp147 90