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Altered dopaminergic profile in the putamen and substantia nigra in restless leg syndrome

M., Boyer, J

MichelsLSchulte-VelsTSchickMO'GormanRLZeffiroTHaslerGet al

doi:10.1016/j.bbalip.2014.07.020

Nature 490 , 5560 (2012)

Figure 4 5.10 Summary of ferroptosis-targeted therapeutic strategies Based on the disease-specific discussions above, ferroptosis-targeted therapeutic strategies can be categorized into three main approaches based on their mechanisms of action: Iron Chelators (e.g., Deferoxamine, Deferiprone) sequester labile iron to limit Fenton chemistry-driven hydroxyl radical generation