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Considering the complex crosstalk between glucose metabolism regulation and other antitumor strategies, in-depth clarification of their crosstalk mechanisms and proposal of appropriate combination strategies are expected to improve antitumor efficacy

In humans, the gene expression pattern of GPX4 was also found to be significantly correlated with proteinuria in human focal segmental glomerulosclerosis samples (26)

Shifts the balance of certain proteins inside cells toward survival signals and reduces activity of a protein involved in cell death, helping protect cells from dying off

Cycle length, side effects, treatment goals, and safety factors should be reviewed by a provider

These organs rely on fatty acids as a fuel source to meet their energy needs

doi:10.1093/annonc/mdi019 177