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MOTS-c MOTS-c is a mitochondrial-derived peptide that influences metabolic regulation and energy utilization

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25 A growing body of evidence suggests that CTR1 transports Cu + , and Ctr1 may function together with metalloreductases such as STEAP and/or DCYTB to transport Cu across the membrane 26,27 (Fig

Although cytotoxic activity is evident at supra-micromolar concentrations, further studies are required to understand the structure-activity relationships across HMCDs

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