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Indeed, age-related clonal expansions of immune cells (clonal hematopoiesis) and inflammaging contribute to CVD risk by boosting inflammatory pathways ( Notably, single-cell studies have already generated clinically relevant findings in CVD that could never be established with bulk techniques (Tang et al., 2019

2 Materials and methods 2.1 Experimental animals Male C57BL/6J mice [specific-pathogen-free (SPF) grade], aged 810 weeks and weighing 2025 g, were obtained from the Laboratory Animal Center of Ningxia Medical University

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The mtROS scavenger MitoQ strongly suppresses RSV production in both primary human bronchial epithelial cells and mouse models 34 , suggesting ROS inhibitors as potential therapeutic tools against RSV