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Multimodal therapy further improved outcomes compared with the results that may be achieved while employing a single active substance or therapy

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These neuromodulators can alter resting membrane potential, firing threshold, and postsynaptic potentials, thereby flexibly adjusting neuronal excitability

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Parabacteroides distasonis showed a significantly higher abundance among HH-R (logFC = 0.4329, p adj = 0.018), but no significant difference was seen in LH-R