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Add-back therapy with low-dose hormones helps offset symptoms, but it adds complexity and cost

Jakubczyk K, Druga A, Katarzyna J, Skonieczna-ydecka K

For example, the entry of glutamine through SLC1A5, combined with its exit through the SLC7A5/LAT1 transporter, allows leucine to enter the cell and trigger mTORC1-mediated cell growth