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The authors reported a case of a patient with cobalamin deficiency who was recommended by her primary neurologist to commence treatment with ocrelizumab, a potent anti-CD20 B-cell depleting monoclonal antibody, after being diagnosed with primary progressive MS

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Some studies suggest that individuals with low levels of B12 are more prone to developing age-related cognitive decline and that supplementation can slow down or even reverse certain symptoms of mental impairment

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