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In hTYR, the hydroxylphenyl group of Arbutin_c, which originally coordinated with CuA, shifts and instead coordinates with CuB during the simulation (Fig

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In breast cancer, alterations in the vascular endothelial growth factor (VEGF) and epidermal growth factor receptor (EGFR) signaling pathways have been linked to the overexpression of c-Jun (Kharman-Biz et al