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Defense mechanisms against free radical-induced oxidative stress involve: (1) preventive mechanisms, (2) repair mechanisms, and (3) antioxidant defenses

Following these steps can help make the process consistent and more comfortable

While these changes may reflect important pathogenic mechanisms, the inference of causality assumed in these hypotheses may not be valid

It plays a pivotal role in protecting cells from damage caused by free radicals and oxidative stress, both of which can adversely impact skin health and accelerate the ageing process

HCV-induced oxidative stress by inhibition of Nrf2 triggers autophagy and favors release of viral particles

Migliavacca Center for Liver Disease, Department of Pathophysiology and Transplantation, University of Milan, (3)Clicon S.r.l