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doi: 10.4161/trns.22281 43 FrancetteA

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48 In another randomized placebo-controlled trial with 170 participants, a combination that included black cohosh, chaste tree, soy, burdock ( Arctium lappa ), and wild yam ( Dioscorea villosa ), taken at a dose of 550 mg twice daily for eight weeks, reduced the frequency and intensity of menopausal night sweats (but not hot flashes)