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Just look at this figure at the website of the organization MitoAction: B12 deficiency usually affects like mitochondrial disorders many organ systems, especially the various parts of the nervous system

Zhong W, Hutchinson TE, Chebolu S, Darmani NA (2014) Serotonin 5-HT3 receptor-mediated vomiting occurs via the activation of Ca2+/CaMKII-dependent ERK1/2 signaling in the least shrew ( Cryptotis parva )

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[DOI] [PMC free article] [PubMed] [Google Scholar] 120.Ambroxol improves lysosomal biochemistry in glucocerebrosidase mutation-linked Parkinson disease cells

Similarly, to test the effect of MUC1-C inhibition, we treated cells that were exposed to 20% or 1% O 2 for 5 days with a volume of GO-203 (Selleckchem) or DMSO as vehicle during the last 24 h of the experiment to reach a final GO-203 concentration of 2.5 M