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Using a 27 G needle attached to a 5 mL Luer-lock syringe, multiple longitudinal and oblique micropunctures depending on plaque size (typically 4 tunnels /cm of fibrotic tissue) are created throughout the plaque

These are different molecules on different scales

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StatPearls

Molecular activity profiling in regenerative and cytoprotective environments

Differentiation of reinfection from relapse in recurrent Lyme disease