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Glutathione- S -transferases (GSTs, E.C.2.5.1.18) are a large family of enzymes that catalyze the conjugation of the reduced glutathione (GSH) to a variety of electrophilic xenobiotics to yield less- or non-toxic derivatives [2], [3]

Pellagra: dermatitis, dementia, and diarrhea

Glucocorticoids are widely known for their anti-inflammatory characteristics, but due to their ubiquitous action profile, their therapeutic use can lead to off-target effects

In an evolutionary distinction, mammalian cells typically operate unidirectionally, i.e., they can convert homocysteine to cysteine, but not the other way round (Finkelstein, 1990)

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Importantly, fish have shared their evolutionary journey with microorganisms living on or within them