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Aberrant glutathione metabolism leads to many diseases such as cancer, Alzheimers disease, and diabetes 27

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overactivation of autophagy may excessively clear healthy mitochondria

Zhong D, Wang R, Zhang H, Wang M, Zhang X, Chen H (2023) Induction of lysosomal exocytosis and biogenesis via TRPML1 activation for the treatment of uranium-induced nephrotoxicity