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the peptide has been shown to promote the healing of tendons, ligaments, muscles, nerves, bones, teeth, corneas, and the endothelium, the lining of blood vessels

Y.JainS.et al (2012)

Another structural protein, called elastin, also reduces, along with a drop in hydration levels

Severely crepey necks with extensive elastin damage may not see dramatic changes

Shoulder arthritis involving cartilage degeneration and bone changes typically does not improve significantly