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10.1016/j.ibneur.2022.10.003 IBRO Neurosci Rep

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Toll-like receptor -four (TLR4) are innate immune activators which upregulate leucocyte infiltration into the myocardium and as a consequence, stimulates the secretion of cytokines, promotes oxidative stress, and releases proteases which in turn induce myocardial infarction or a heart attack, ischemic-reperfusion injury, myocarditis and heart failure

The inflammatory cytokines like IL-6 activate STAT3, and STAT3 in turn regulates IL-6

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Its signature vibrant blue color arises from the presence of copper ions, which are essential for various enzymatic reactions within the skin