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Description

For semaglutide, with a half-life of approximately one week, this means a 5-7 week gap

Ethical complexities arise in trial design, particularly concerning vulnerable groups like incarcerated individuals and people living with HIV, requiring stringent safeguards and specialized protocols (Riste et al., 2021)

Avoiding these pitfalls isn't complicated

The STEP 1 trial, published in the New England Journal of Medicine in 2021, enrolled 1,961 adults with obesity and randomised them to 2.4mg weekly semaglutide or placebo for 68 weeks