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Funding Open Access funding enabled and organized by CAUL and its Member Institutions

281,282,295 Beyond the important role in DNA repair, PARP-1 also acts as a modulator of NF-B, inducing the downstream CCL2-CCR2 signaling, which is required for the recruitment of NK cell to the infection site and viral control

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It also plays a crucial role in detoxifying harmful substances, supports the immune system, and helps in the metabolism of fats and proteins

AlphaFold2 multimer 65 was used through the implementation in ChimeraX 60

Intravenous (IV) delivery changes the game entirely