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Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method

Despite the exposure of mitochondria to the production of oxidants, the presence of an effective antioxidant system, of which mitochondrial GSH (mGSH) is a key component, prevents or repairs oxidative damage that occurs during normal aerobic metabolism [57]

During these periods of oxidative stress, levels of GSSG may rise, prompting the induction of GGT to facilitate the recycling of precursor amino acids for GSH synthesis to maintain a balanced GSH-to-GSSG ratio [29,87]

Enhancing GSH synthesis SLC7A11 is an essential molecule that limits the Cys transport rate, thus restricting the synthesis of GSH

Johnson RR, Cranston HJ, Chaverra ME, Dyer WE (1995) Characterization of cDNA clones for differentially expressed genes in embryos of dormant and non-dormant Avenua fatua (L.) caryopses