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The SNP rs755622 is associated with immune activation in glioblastoma

2.15 C57BL/6 mice insights into Alzheimers disease research C57BL/6 mice are the most extensively used models in AD research, owing to their exceptional genetic stability, robust breeding capabilities, and adaptability to laboratory conditions

The knockdown of Caspase-1 could decrease the protein level of GSDMD and increase the ubiquitination levels of GSDMD but did not affect GSDMD mRNA, indicating that Caspase-1 might not directly regulate GSDMD