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The study protocol was reviewed and approved by the Institutional Review Board of Beijing Huilongguan Hospital

The patient denies any contraindications to GIP/GLP-1 RA

coli O44K74 strain, when comparing anaerobic and aerobic conditions for the biotransformation using cells grown under anaerobic conditions, productivities of 0.18 g L -1 h -1 , and 0.21 g L -1 h -1 (34 and 39% molar yield) respectively, were obtained [14]