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HuangZXHeXRDingXYChenJHLeiYHBaiJBet al

A valence-engineered self-cascading antioxidant nanozyme for the therapy of inflammatory bowel disease

Absorption is fundamentally difficult due to its naturally limited bioavailability

This study shows that MYC downregulation of mir-23a/b relieves repression of GLS as part of the oncogenic reprogramming of glutamine metabolism

Animal setup Anaesthesia was induced with a bolus of 4% isoflurane mixed with air after what a single bolus of medetomidine in saline (0.1 mg/ml) administered (0.2 mg/kg, s.c.) followed by a continuous infusion (0.4 mg/kg/h, s.c.) with minimal isoflurane administration (0.2% in air containing 35% O 2 )

The novel material was compared with a castor oil derived-polyurethane prepared with a commercially available fossil-based isocyanate counterpart