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10.4161/auto.20958 15 AndreeffM.KellyK

63 , 97-xx98 (2021)

The interaction of these two variables determines the age of onset and the rate of disease progression

For example, the Mcl-1/Bax ratio increases following GM-CSF stimulation in neutrophils from individuals of a younger age, whereas this ratio remains unchanged in neutrophils from older individuals [132, 133]

Studies have demonstrated that TBI-associated mRNA signature and enhanced type 1 interferon signaling are apparent in cortical microglia after TBI (Witcher et al., 2021)