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These results were observed after intermittent treatment over several weeks

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Taking Pramlintide as an example, it is a synthetic analog of human insulin composed of 31 amino acids

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[10] The first amylin analogue to reach the clinic, pramlintide, demonstrated that the pathway could be drugged, but native-style amylin analogues are short-acting and were used as multiple-daily injections, which limited their appeal for weight management