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In fact, the European Male Ageing Study, often cited in research, found that approximately 5% of men aged between forty and seventy live with hypogonadism the medical term for testosterone deficiency [8]

13 In B12 deficiency, methionine synthase cannot function properly, causing methylfolate to accumulate while other folate forms needed for DNA synthesis (5,10methyleneTHF / THF) become depleted

Extremes matter: patients under 50 kg often do well at the lower end, patients over 100 kg may sit at the upper end of standard ranges

Sep-Oct 2014;16(72):265-9