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Among the developed prodrugs, the lack of activity was confirmed only for D-glucose-conjugated prodrug of 7-chlorokynurenic acid (133, 134), glycosyl prodrugs of dopamine (135) and ibuprofen prodrugs (145)

MarjaskaMMcCartenJRHodgesJHemmyLSGrantADeelchandDKet alRegion-specific aging of the human brain as evidenced by neurochemical profiles measured noninvasively in the posterior cingulate cortex and the occipital lobe using 1H magnetic resonance spectroscopy at 7 T

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Interestingly, no lactate 13 C-labelling was detected during the 1-hour timeframe of the infusion, which was due to the use of medetomidine in these experiments, known to prevent lactate build up and labelling 43 compared to isoflurane 44 (Fig.3b)

Bioinformatics 21 , 39403941 (2005)