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Description

Both employed an oral AOD-9604 formulation [2]

DNA-binding of drugs used in medicinal therapies

Evidence of the COVID-19 virus targeting the CNS: tissue Distribution, Host-Virus Interaction, and proposed neurotropic mechanisms

However, a lower mitochondrial DNA (mtDNA) copy number is associated with poorer ageing outcomes, particularly in individuals over 50 years of age, where mtDNA declines more rapidly than in HIV-negative counterpartseven among those with well-controlled HIV on ART [175]

The nuclear factor erythroid 2-related factor 2 (Nrf2) is well-known due to its capability in improving antioxidant defense system via targeting down-stream mediators including heme oxygenease-1 (HO-1), superoxide dismutase (SOD) and NADPH quinone reductase 1 (NQO1) (Song et al., 2020)