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36 By reviewing the evidence of pharmacological therapy in conjunction with surgical treatments, the paucity of effective treatments for patients with fistulising CD is apparent and represents a significant unmet need

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Interestingly, the IDH1 mutant glioma was the tumor that did not conform to this trend, suggesting that it has a distinct metabolic profile from the primary GBMs, but still harbors an astrocyte-like subpopulation that is selectively vulnerable to ferroptosis

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