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As an FDA-approved anti-cancer drug, romidepsin holds potential as a pharmacological treatment that corrects epigenetic abnormalities in ASD

However, mito-TEMPO treatment significantly ( P 0.05) increased the activities of mtGSH (17.24%), mtGPx (72%), mtGR (86.66%) and MnSOD (36.36%) in 5-FU + Mito-TEMPO group as compared to 5-FU group ( Table 2 )