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10.1371/journal.pone.0162590 41 LueticK.SucicM.VlainicJ.HalleZ

Expected timeline: Variable based on procedures performed

Ingredients: Vitamin C (as ascorbic acid) Setria L-Glutathione (reduced) L-Cysteine Hydrochloride Other Ingredients: vegetable cellulose (capsule), microcrystalline cellulose, stearic acid, silica

Patients aged 18 or older with AIS within 14 days, NIHSS score 6, and a pre-stroke mRS of 0 or 1 were included

This preparation permits intravital imaging of the unperturbed meninges and brain parenchyma

Intriguingly, appropriate linkers differed among the dimeric macrocycles: (1) aML5 yielded the highest activity when dimerized by PEG3 (aML5-PEG3) and was nearly inactive when dimerized by the other two linkers (Fig