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Additionally, the RNA-sequencing of L-Cn-treated PBMCs and the GSE62595 dataset can only show the transcriptome changes at the overall level, further studies on exploring the modulation mechanism of L-Cn on a single set of cells should be taken to dissect the related signaling pathway

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However, a review indicates that peppermint and its main constituentspulegone, menthone, menthol, and menthofuranexhibit mild toxicity

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