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doi: 10.3389/fphar.2025.1697986 Received 03 September 2025 Revised 29 September 2025 Accepted 31 October 2025 Published 20 November 2025 Volume 16 - 2025 Edited by Yunpeng Yi, Shandong Academy of Agricultural Sciences, China Reviewed by Mariana Carmen Chifiriuc, University of Bucharest, Romania Ermin Schadich, Palack University, Olomouc, Czechia Updates Copyright 2025 Osei Duah, Amankwah, Ampong, Brown, Tettey, Acheampong, Awuku and Danquah

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One of the most well-established properties of GSH is its role in maintaining redox homeostasis, but it is also emerging as a mediator of redox signaling through mechanisms such as protein S-glutathionylation and/or GSNO-mediated protein S-nitrosylation (Zhang and Forman, 2012)