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GHK-Cu (Glycyl-L-Histidyl-L-Lysine copper complex, also known as Copper Tripeptide-1) is a naturally occurring tripeptide bound to a copper ion (Cu)

The research team of Frias et al designed a 32-week, randomized, double-blind, parallel-group, active control trial that included adults with a diagnosis of type 2 diabetes and a body mass index of 27 and HbA1C levels ranging from 7.5% to 10% despite a daily dose of metformin

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NUPR1 is emerging as a potential target in oncology, including for lung cancer 66,77,78 , because NUPR1 supports survival, therapy resistance, and stress adaptation of tumor cells 64,79,80

Western blot analysis showed that high glucose upregulated the expression of Hif3a, cleaved parp, Bad, Bax, Caspase 9, cleaved Caspase 9 (37 kDa), and cleaved Caspase3 in HT22 cells (Figure 8C)