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*Based on the protocol-specified final OS analysis Initial Treatment in Combination with Cisplatin The efficacy of ALIMTA was evaluated in Study JMDB (NCT00087711), a multi-center, randomized (1:1), open-label study conducted in 1725 chemotherapy-naive patients with Stage IIIb/IV NSCLC

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When exposed to the cold temperature, the PCPA-treated mice experienced a sharp drop in body temperature, while the control mice maintained a normal temperature