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PEA is an endogenously produced lipid mediator that helps maintain neuroimmune balance and inflammatory tone

At the 2017 International Lyme and Associated Diseases Society conference in Boston, I heard about curcumin, also known as turmeric, a member of the ginger family that acts as an anti-inflammatory and which has many uses to help mitigate Herxheimer reactions

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Altern Med Rev 6:4509, PMID: 11703165 Jammes Y, Steinberg JG, Mambrini O, Brgeon F, Delliaux S (2005) Chronic fatigue syndrome: assessment of increased oxidative stress and altered muscle excitability in response to incremental exercise