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MDMA and tramadol or tapentadol co-administration causes serotonin-independent neurological damage DOI: Keywords: MDMA, tramadol, tapentadol, serotonin, in vitro, acute neurotoxicity Abstract The simultaneous consumption and misuse of different drugs, including 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) and opioids, raise concerns about fatal intoxications, as a result of increased serotonin levels

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10.1186/s40478-019-0737-z [DOI] [PMC free article] [PubMed] [Google Scholar] Lewerenz J., Maher P

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At least 20 animals were quantified in each condition ( b,d,h,j )