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the lower the gauge number, the bigger or thicker the hole

This is particularly important if you are part of any of the groups considered to be at high risk of B12 deficiency, including alcoholics, smokers, those on diabetes drugs, adults over 65, those with gastrointestinal disorders and those who have had surgery relating to the digestive tract

Theyre usually given weekly, then monthly for maintenance, Dr

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So while taking out of date supplements shouldnt cause you to feel ill, it could be a waste of your time, as the capsules will likely have lost the the percentage of dietary supplement ingredients listed on the label