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HIF-1 is upregulated in PASMCs of chronic cobalt chloride-induced PAH rats, which phosphorylates Drp1 by increasing Cyclin B/CDK1, subsequently leading to increased expression of the PDHK2 and PDHK4 genes, resulting in increased lactate production and promotion of glycolysis

69 Participants were premedicated with clonidine and midazolam, intubated using propofol and atracurium, and mechanically ventilated

Obtain a complete blood count at the beginning of each cycle

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Detoxifying the body: It binds to harmful substances, helping the liver remove them efficiently

Genet Med 10, 369384 (2008)