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In disease states such as atrophic gastritis and pancreatic insufficiency, low serum B12 concentrations arise because digestion of protein-bound B12 is compromised

A similar phenomenon has been observed in baboons but only after a protracted dosing period (6 months) at higher dose levels (335 mg/kg/day or more)

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C., Daruwala, R., Park, J

Their ability to act in a targeted manner means theyre often able to provide the same benefits as traditional drugs or hormones and sometimes with fewer side effects

As you see, at any age, pernicious anemia is related to impaired absorption of B12 because of IF issues