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Rarely reported symptoms may include mild skin reactions, gastrointestinal disturbance, or headache, typically following high-dose intramuscular injections

The injection site When people complain about arm or leg pain after B12 injections, its often because of intramuscular delivery

For example, growth hormone is implicated in activating bone turnover, increasing body lean mass, and reducing adiposity

Weve looked into how vitamin B12 and different drugs, like proton pump inhibitors and metformin, interact

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For patients without absorption disorders, high-dose oral supplements of 1,000 to 2,000 mcg daily have been shown to be comparably effective at correcting mild to moderate deficiency at lower cost and greater convenience.