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Adenosine Production by Canonical and Alternative Ectoenzymatic Pathways The purinome exploits the metabolically reprogrammed niche to generate extracellular ADO which is locally produced by the multicellular network (Figure 2)

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This study found that the treatment is most effective in cases of mild to moderate levels of osteoarthritis

anserina , gene clusters of het-S / nwd2 are present in the genomes of dozens of fungal species (Saupe and Daskalov, 2012)