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The above data suggest that redox imbalance as a result of repeated treatment with a glutathione synthesis inhibitor (BSO) administered alone or in combination with a DA reuptake inhibitor (GBR 12909) during early postnatal development, may be an important factor reducing the BDNF protein levels or mRNA expression in the frontal cortex and in the hippocampus in adulthood

Glutathione IVs have been used in clinical settings for patients with chronic liver disease, including nonalcoholic fatty liver disease, or liver poisoning

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Primer sequences are in Supplementary Table 2

European respiratory society statement for defining respiratory exacerbations in children and adolescents with bronchiectasis for clinical trials

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